CURRENT NEWS
October 26th 2010
Total Scientific Expands into New Premises
Total Scientific, a CRO specialising in biomarkers, has moved into custom-designed units in the new Maia building at Babraham Research Campus, marking the latest stage in its expansion.
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Our portfolio company, Total Scientific (TSL) has moved into enlarged accommodation in the newly opened Maia building on the Babraham Research Campus, just south of Cambridge, UK. The new accommodation has been custom-designed to support cell culture as well as a wide range of in vitro biology needs, including TSL's Luminex platform. A suite of offices complement the expanded lab accommodation.
Commenting on the move at a lunch held to mark the expansion, David Mosedale, CEO at TSL, said "We are delighted to be able to stay on the Babraham campus, while at the same time expanding significantly our capacity to support our growing customer base. The state-of-the-art new labs match our core values of quality and excellence."
TSL now has 8 employees, with sales forecast to grow by at least 20% in 2010 despite challenging global economic conditions. The company specialises in provision of biomarker services to diagnostics and drug development companies, including assay design and validation, bioanalysis, bespoke clinical trials, biobanking and data analysis services.

May 26th 2010
FXT Raises €10M
Funxional Therapeutics has announced the closing of its Series B financing round, raising a further €10M to support the clinical development of FX125L
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unxional Therapeutics (FXT) have raised a further €10M in a series B round, with new investor Ventech joining existing investors Index Ventures and Novo A/S.
FXT is developing a series of novel anti-inflammatory agents which block chemokine-induced leukocyte migration, with am initial focus on respiratory
diseases. Their lead compound, FX125L, successfully completed Phase I earlier in 2010. The new funds will be used to support the further clinical
development of this compound.
Karl Naegler has joined the Funxional Therapeutics Board, representing Ventech.
Download the full press release...

January 8th 2010
FX125L Phase I programme completed
Our portfolio company Funxional Therapeutics today announced the successful
completion of the Phase I programme for its lead molecule, the
broad-spectrum chemokine inhibitor FX125L.
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On 8th January 2010, Funxional Therapeutics Ltd, the Cambridge-based
clinical-stage drug development company in our portfolio, issued a press
release announcing the successful completion of Phase I clinical development
of its lead compound FX125L. This compound is a broad-spectrum chemokine
inhibitor being developed initially for respiratory indications, including
asthma. It is a once daily oral anti-inflammatory compound, with an
attractive therapeutic profile.
Following the announcement of the successful single ascending dose study in
healthy volunteers in July 2009, which was also presented to the American
College of Asthma, Allergy and Inflammation meeting in Miami in November 09,
FXT have now shown that the compound was well tolerated following daily
dosing for up to 10 days, even at the highest dose tested.
FXT aim to begin Phase II testing in various inflammatory indications in
2010.
LINK : FXT125L PHASE 1 COMPLETION PDF
